The researchers were able to conclude, after experimenting on rats, that a certain molecule compound called nobiletin, specifically found in sweet oranges and tangerines, was able to bring down obesity significantly.
The study published in the Journal of Lipid Research found that a comparison between two types of rats was able to demonstrate how exactly this happened. Strangely enough, the scientists could not figure out the pathway of this underlying mechanism. But they were delighted to find a potential therapy for obesity.
The first group of rats given high-fat and high-cholesterol diets were also given nobiletin, while the other group was only fed the high-fat diet. The former bunch of rats had changed and become leaner, and the levels of insulin resistance had dropped. The second bunch of rats who were not given nobiletin did not improve their health.